25th July 2019 – Global In
Situ Hybridization (ISH) Market is expected to reach USD 1.84 billion
by 2025. In Situ Hybridization (ISH) is a type of hybridization a method that
permits for specific localization of an exact segment of nucleic acid inside a
histologic section. That means it involves the use of labeled RNA probes or
labeled DNA probes to detect complementary DNA or RNA targets in cytologic
preparations or tissue sections. Synthetic oligonucleotides (PNA, LNA),
Double-stranded DNA (dsDNA) probes, RNA probes (riboprobes), and
Single-stranded DNA (ssDNA) probes are the majorly used ISH probes.
The In Situ Hybridization (ISH)
industry is estimated to grow at a significant CAGR of 7.3% over the future
period as the scope and its applications are rising enormously across the
globe.
It can be labeled using two major
techniques like Non-radioactive labels and radioactive isotopes. A labeled RNA
or DNA probe can be used to hybridize to a known target DNA or mRNA sequence
within a sample. This labeled RNA or DNA probe can then be detected by using an
antibody to detect the label on the probe. In Situ Hybridization (ISH) Market
is segmented based on product type, technology, probe type, application, end
use, and region.
Services, instruments, software, and
kits & probes are the product types that could be explored in In Situ
Hybridization (ISH) in the forecast period. The instruments sector accounted
for the largest market share of In Situ Hybridization (ISH) industry and is
estimated to continue its dominance in the upcoming years. This may be because
of high demand from research laboratories and diagnostic centers. Also, these
instruments are easy to handle, cost-efficient, and portable these factors may
lead the sector in coming years. However, kits & probes sector is estimated
to grow at highest CAGR in the coming years.
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The enhanced technology used in In Situ
Hybridization (ISH) is Chromogenic In Situ Hybridization (CISH) and Fluorescent
In Situ Hybridization (FISH) that could be explored in the future period. RNA
probe and DNA probe are the two main types of probes that could be explored in
In Situ Hybridization (ISH) in the foremost period. The DNA probes sector is
estimated to account largest revenue shares of In Situ Hybridization (ISH) in
the coming years. Whereas, RNA sector is estimated to grow at highest CAGR in
the coming years.
The market may be categorized based on
applications like infectious diseases, cancer, developmental biology,
cytogenetics, and others that could be explored in the future period. Cancer
sector accounted for the largest market share of In Situ Hybridization (ISH)
and is estimated to grow at highest CAGR in the coming years. The reason could
be growing occurrence of cancer and rising research in this sector. However,
cytogenetics sector is estimated to grow at fastest pace in the coming years.
End users like academic institutes,
research & diagnostic laboratories, contract research organizations (CROs),
and others could be explored in In Situ Hybridization (ISH) Market in the
forecast period. The research & diagnostic laboratories sector accounted
for the largest market share of In Situ Hybridization (ISH) and is estimated to
lead the overall market in the coming years. This may be because of growing
applications of molecular cytogenetics in diagnostics, rising use of enhanced
technology in genomics and molecular cytology, and rising initiative in cell
research. However, CROs segment is estimated to grow at fastest pace in the
coming years.
Globally, North America accounted for
the largest market share of In Situ Hybridization (ISH) and is estimated to
lead the overall market in the upcoming years. The reason behind the growth of
overall market could be government involvement for development of novel
diagnostic tools, availability of research funds, and developed research centers.
The United States is a major consumer of In Situ Hybridization (ISH) in this
region.
Instead, Europe and the Asia Pacific are
also estimated to have a positive influence on the future growth. Europe is the
second largest region with significant market share. However, Asia Pacific is
estimated to grow at fastest pace with the highest CAGR in the foremost period.
The aspects that may be ascribed to the growth comprise, growing awareness
regarding advantages of In Situ Hybridization (ISH) technology in diagnostics
and government initiative in R&D investments in the field of molecular
biology. The developing countries like India and China are the major consumers
of In Situ Hybridization (ISH) industry in the region.
The key players of In Situ Hybridization
(ISH) Market are Oxford Gene Technology, Thermo Fisher Scientific, Advanced
Cell Diagnostics, Inc., Leica BiosystemsNussloch GmbH, NeoGenomics
Laboratories, Inc., BIOVIEW, Bio-Rad Laboratories, Inc., Agilent Technologies,
PerkinElmer, Inc., and Merck KGaA. These players are concentrating on inorganic
growth to sustain themselves amongst fierce competition. As such, mergers,
acquisitions, and joint ventures are the need of the hour.
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