30th July 2019 – Global Vaccine
Contract Manufacturing Market size is expected to reach USD 4.0 billion
by 2025, A vaccine provides active acquired immunity to a disease. The demand
for vaccine contract manufacturing is increasing in the market. Vaccine
manufacturing is a complex process, in which effectivity, safety and
consistency are the most important part for the manufacturers. It offers many
services such as production process, cell line development, construction &
operation of manufacturing product, process optimization, fermentation and
analytical characterization, which fuels the market growth in the coming years.
The vaccine contract manufacturing market registering a CAGR of 9.3% in the
upcoming period as the scope, product types, and its applications are
increasing across the globe.
Vaccine contract services offer
cost-saving benefits to their clients. Also, they help to save time in
operations & management of a research and production facility. The growing
demand for vaccine development from the private sector as well as governments
in developing and industrialized countries is expected to witness significant
growth of the market in the coming years.
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In the market, various types of vaccines
are available such as inactivated vaccines, attenuated vaccines, toxoid-based
vaccines, subunit-based vaccines, DNA-based vaccines, recombinant vector
vaccines, synthetic vaccines and others. The “attenuated vaccines” is expected
to hold the large market share in the upcoming period due to their ability to
elicit strong and antibody responses. These vaccines offer lifetime immunities
with just one or two doses. Moreover, proper handling conditions, especially
with respect to storage and maintenance will continue to drive the segment in
the coming years.
In addition, in the market some single as
well as combination vaccine are available. The single vaccine such as influenza
virus, ebola virus, chickenpox, smallpox, polio, tetanus, tuberculosis and
others could be explored in vaccine contract manufacturing industry. The
factors that play an important role in the growth of market include increasing
demand, growing population, increasing urbanization & industrialization,
growing pharmaceutical industry, increase in the number of countries demanding
the introduction of vaccines, stringent government rules & regulations and
increasing awareness about vaccination & its benefits in developing
countries. Moreover, increasing prevalence of various bacterial and viral
infections is a main factor drive the growth of the vaccine contract
manufacturing market in the next couple of years.
However, high cost of vaccination,
regulatory challenges and patent expiration in recent times are negatively
impacting the growth of vaccine contract manufacturing industry. The market is
widely analyzed based on different regional factors such as gross domestic
product (GDP), demographics, acceptance, inflation rate and others. The market
is categorized based on vaccine type, product type, workflow, application and
geography.
The market is classified into workflow
such as downstream and upstream. The “downstream” segment is further segregated
into fill & finish operations, packaging and analytical & QC studies
whereas the segment “upstream” is segmented into mammalian expression systems,
yeast expression systems, bacterial expression systems, baculovirus/insect
expression systems and others. Vaccine production requires skilled personnel
for downstream as well as upstream processing. The “downstream” segment is
expected to witness significant growth in the coming years owing to the robust
demand for downstream processing and sophisticated equipment for efficient
product recovery.
North America is accounting large market
share in the years to come owing to widespread manufacturing of vaccines in
this region, coupled with growing presence of large number of biopharmaceutical
facilities. State and the other laws pertaining to development of vaccines
& other biologics, particularly in Canada and U.S. are expected to boost
the market growth in this region. On the other hand, Asia Pacific is projected
to grow at a higher CAGR in the next couple of years due to growing population,
improving infrastructure in several developing countries, and growing
pharmaceutical industry.
The key players contributing to the
robust development of the vaccine contract manufacturing market include Lonza,
Paragon Bioservices Inc., Ajinomoto Althea Inc., FUJIFILM Diosynth
Biotechnologies U.S.A. Inc., Merck KGaA, Cytovance Biologics, Catalent Inc.,
IDT Biologika GmbH, Albany Molecular Research Inc., PRA Health Sciences, ICON
plc., Pharmaceutical Product Development, LLC, and Cobra Bio. The major market
players are focusing on inorganic growth to sustain themselves amidst fierce
competition. As such, mergers, acquisitions, and joint ventures are the need of
the hour.
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